Catalunya – BIO

The Catalunya-BIO node, led by researcher Klaus Langohr (Universitat Politécnica de Catalunya), is formed by 36 researchers. Its main lines of research focus on Biostatistics and Bioinformatics.

Researchers participating in the node

Principal Investigator: Klaus Langohr (Universitat Politécnica de Catalunya)

View all members

Main lines of investigation

The Catalunya-BIO node is formed by researchers whose research areas are mainly Biostatistics and Bioinformatics. The research projects of the members of the node deal with new methodological developments in survival analysis, clinical trials, multivariate statistics, mathematical modeling of metabolic systems, integrative analysis of high-throughput data (genomics, proteomics and metabolomics), integration of survival analysis methods and clinical statistics, proteomics and metabolomics), in the integration of survival analysis methods and genetic statistics and are characterized by real problems arising in clinical medicine, biomedicine, genomics, epidemiology and pharmacoeconomics, among others. Since 2020, several members have been working with multistate models to study the evolution of patients hospitalized by COVID-19 within the DIVINE project (2020PANDE00148).

Among the current lines of research of this node (see poster):

  • Composite endpoint analysis with time-to-event response or binary response.
  • Bioequivalence testing of drugs with high variability.
  • Publication guidelines and peer-review.
  • Analysis methodologies in the context of clinical trials: Design and power improvement, analysis for repeated measures and missing values.
  • Analysis for complex censoring patterns, in particular for double censoring and for censoring in an interval.
  • Joint modelling with longitudinal and time-to-event data.
  • Multivariate methods for the integration of omics data.
  • Kernel methods applied to genomics.
  • Methods for microbiome analysis.
  • Use of biological information for comparative analysis.
  • Multi-state models.

Institutions present in the node

Entities and groups with which it collaborates

Fundació Lluita contra la SIDA (FLS) del Hospital Universitari Germans Trias i Pujol

Programa HIVACAT del Hospital Universitari Germans Trias i Pujol

Programa de Investigación en Neuropsicofarmacología del Institut de Investigación del Hospital del Mar (IMIM)

LIRAD: Laboratori de Immunobiologia per Recerca i les Aplicacions Diagnòstiques

Grupo de Neuroimmunología Clínica del Instituto de Investigación del Hospital Universitari de Vall d’Hebron

Departamento de Salud Generalitat de Catalunya

Servei Català de la Salut

Dana-Farber Cancer Institute

Universitat Rovira i Virgili

List of node members

  • Klaus Langohr

    Principal InvestigatorComité EjecutivoUniversitat Politécnica de Catalunya
  • Albert Sorribas Tello

    Universitat de Lleida
  • Alberto Marin Sanguino

    Universitat de Lleida
  • Alexandre Sánchez Pla

    Universitat de Barcelona
  • Andrea Toloba López-Egea

    Universitat Politécnica de Catalunya
  • Carles Forné Izquierdo

    Universitat de Lleida
  • Carles Serrat i Piè

    Universitat Politécnica de Catalunya
  • Concepción Arenas Sola

    Universitat de Barcelona
  • Cristian Tebé Cordomí

    Institut d’Investigació Biomédica de Bellvitge (IDIBELL)
  • Daniel Fernández Martínez

    Universitat Politécnica de Catalunya
  • David Blanco de Tena Dávila

    Universitat Internacional de Catalunya
  • Erik Cobo Valeri

    Universitat Politécnica de Catalunya
  • Esteban Vegas Lozano

    Universitat de Barcelona
  • Ester Vilapriñó Terré

    Universitat de Lleida
  • Guadalupe Gómez Melis

    Universitat Politécnica de Catalunya
  • Guillermo Villacampa Javierre

    Vall d’Hebron Institut d'Oncologia
  • Iván David Benítez Iglesias

    Institut de Recerca Biomédica de Lleida (IRBLLEIDA)
  • Joan Valls Marsal

    International Agency for Research on Cancer (IARC)
  • Jordi Cortés Martínez

    Universitat Politécnica de Catalunya
  • Jordi Ocaña Rebull

    Universitat de Barcelona
  • José Antonio González Alastrué

    Universitat Politécnica de Catalunya
  • María Luz Calle Rosingana

    Universitat de Vic – Universitat Central de Catalunya
  • Marta Bofill Roig

    Medical University of Vienna
  • Martí Casals Toquero

    Universitat de Vic – Universitat Central de Catalunya
  • Mireia Besalu Mayol

    Universitat de Barcelona
  • Montserrat Martínez Alonso

    Institut de Recerca Biomédica de Lleida (IRBLLEIDA)
  • Montserrat Rué Monné

    Universitat de Lleida
  • Natàlia Vilor Tejedor

    BarcelonaBeta Brain Research Center (BBRC)Center for Genomic Regulation (CRG)Erasmus Medical Center
  • Nuria Pérez Álvarez

    Fundació Lluita contra la Sida
  • Pedro Esteban Sandoval Alvarado

    Institut de Recerca Biomédica de Lleida (IRBLLEIDA)
  • Ramon Oller Piqué

    Universitat de Vic – Universitat Central de Catalunya
  • Rui Carlos Vaqueiro de Castro Alves

    Universitat de Lleida
  • Sara Tous Belmonte

    Institut Catalá d’Oncología
  • Susana Pérez Álvarez

    Biokit Research & Development SL
  • Urania Dafni

    University of Athens
  • Xavier Piulachs Lozada-Benavente

    Universitat Politécnica de Catalunya
  • Yovaninna del Carmen Alarcón Soto

    Fundació Lluita contra la Sida