Practical Course on Bioinformatics and Network Biology: from genomic data to profiles, networks and pathways
Practical Course on
BIOINFORMATICS AND NETWORK BIOLOGY:
from genomic data to profiles, networks and pathways
22,23,24 – June – 2011
Centro de Investigación del Cancer (CiC-IBMCC, CSIC/USAL), Salamanca, SPAIN
Practical Course on Bioinformatic tools and methods to analyse data from genomic studies, to build biomolecular profiles and networks derived and to explore pathways associated. Analyses of multiple genome-wide microarray data to detect significant changes in expression of genes, exons, miRNAs or copy number alterations. Critical steps to achieve robust data annotation and functional enrichment analyses. First steps for Next Generation Sequencing (NGS) data anlaysis and comparison with microarrays. Use of tools to unravel the biological information enclosed in selected gene lists, to build networks derived and to explore biological pathways associated. Analysis of molecular interactions using PSIMEx databases and tools.
Day 1 – 22.June.2011 (Wednesday)
Topic 1: Genomic and transcriptomic profiling: microarray data analysis (focus on Affymetrix).
Gene arrays, exon arrays, miRs arrays, copy number arrays.
Bioconductor-R tools, GEO, Gene Expression Atlas, GATExplorer.
Day 2 – 23.June.2011 (Thursday)
Topic 2: First steps for Next Generation Sequencing (NGS) data analysis.
Platforms (454, Illumina, SOLiD), Bioconductor-R tools for NGS (RNAseq).
Topic 3: Bioinformatic tools for functional annotation and analysis of selected gene lists.
Enrichment Analysis, DAVID, GSEA, Blast2GO, GeneTerm Linker, iHop.
Day 3 – 24.June.2011 (Friday)
Topic 4: Construction of gene/protein networks and exploration of pathways using bioinformatic tools.
Molecular Interactions (PSIMEx-PSICQUIC), Visualization (Cytoscape, Ingenuity), Pathways (Reactome, KEGG), Disease Networks (NetClassifier, DisGeNET).
Dr. Javier De Las Rivas (director) (Centro de Investigación de Cáncer CiC-IBMCC, CSIC / USAL, Salamanca)
Dr. Alfonso Valencia (Instituto Nacional de Bioinformática INB, Centro Nac. de Investig. Oncológicas CNIO, Madrid)
Dr. Federico Moran (Instituto Nacional de Bioinformática INB y Universidad Complutense, Madrid)
Dr. Sandra Orchard (European Bioinformatics Institute EBI, Cambridge, UK)
With special support given by PSIMEx EU project (http://www.psimex.org) and INB (http://www.inab.org).
REGISTRATION: The price is 290 Euros (before 31.May.2011) 320 Euros (after 31.May.2011). It includes registration, documention, full practicals and meals. If you are interested please sent an e-mail as soon as possible for pre-registration to: firstname.lastname@example.org Bioinformatics and Functional Genomics, CiC-IBMCC (CSIC/USAL), Salamanca. IMPORTANT: Bring a personal computer (laptop) for the practicals. Wi-Fi internet connection will be available.